Journal of cardiovascular electrophysiology
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J. Cardiovasc. Electrophysiol. · Jul 2001
Randomized Controlled Trial Comparative Study Clinical TrialVERDICT: the Verapamil versus Digoxin Cardioversion Trial: A randomized study on the role of calcium lowering for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation.
Many relapses of atrial fibrillation (AF) occur, especially during the first week(s) after electrical cardioversion (ECV). The aim of the present study was to compare in a randomized design the efficacy of verapamil (intracellular calcium lowering) versus digoxin (calcium increasing) for maintenance of sinus rhythm after ECV. ⋯ Stand-alone intracellular calcium lowering by verapamil around ECV does not enhance cardioversion outcome.