Journal of cardiovascular electrophysiology
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J. Cardiovasc. Electrophysiol. · Dec 2006
Arrhythmogenesis in the developing heart during anoxia-reoxygenation and hypothermia-rewarming: an in vitro model.
The spatio-temporal pattern of arrhythmias in the embryonic/fetal heart subjected to a transient hypoxic or hypothermic stress remains to be established. ⋯ In the embryonic heart, arrhythmias mainly originated in the sinoatrial tissue and resembled those observed in the adult heart. Furthermore, oxygen readmission was by far more arrhythmogenic than rewarming and the chronotropic, dromotropic, and inotropic effects were fully reversible.
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J. Cardiovasc. Electrophysiol. · Dec 2006
Editorial CommentAtrial fibrillation: much heat, a little light.