Journal of cardiovascular electrophysiology
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J. Cardiovasc. Electrophysiol. · Jan 2013
Randomized Controlled Trial Multicenter StudyCost-effectiveness of cardiac resynchronization therapy in the MADIT-CRT trial.
The Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT) trial demonstrated that cardiac resynchronization therapy (CRT) when added to the implantable cardiac defibrillator (ICD) reduces risk of heart failure or death in minimally symptomatic patients with reduced cardiac ejection fraction and wide QRS complex. ⋯ In minimally symptomatic patients with low ejection fraction and LBBB, CRT-ICD is cost effective within 4-year horizon when compared to ICD-only.