Coronary artery disease
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Coronary artery disease · Jan 2012
Obstructive sleep apnea is common among patients referred for coronary artery bypass grafting and can be diagnosed by portable monitoring.
Obstructive sleep apnea (OSA) is common among patients with coronary artery disease. However, OSA remains largely under recognized. The lack of clinical suspicion and difficulties to access full polysomnography (PSG) are limiting factors. The aim of this study was to evaluate, among patients referred to coronary artery bypass grafting (CABG): (i) the prevalence of OSA, (ii) the association of OSA with clinical symptoms, (iii) the performance of overnight unattended portable monitoring (PM) as an alternative method for the diagnosis of OSA. ⋯ OSA is strikingly common among patients referred for CABG. The Berlin questionnaire, but not symptom of excessive daytime sleepiness is a useful tool to screen OSA. PM is useful for the diagnosis of OSA and therefore is an attractive tool for widespread use among patients with coronary artery disease.
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Coronary artery disease · Jan 2012
Relation of red cell distribution width with the presence, severity, and complexity of coronary artery disease.
Red cell distribution width (RDW) is a measure of the heterogeneity of cell size in the peripheral blood and has been shown to be an independent correlate of adverse outcomes in healthy participants and in some cardiac conditions. We examined the association between RDW and the complexity of coronary artery disease (CAD). ⋯ RDW is a readily available clinical laboratory value that is associated with both the presence and the complexity of CAD.
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Coronary artery disease · Jan 2012
Clinical TrialIncidence, predictors, and 30-day outcomes of new-onset atrial fibrillation after primary percutaneous coronary intervention: insight into the RISK-PCI trial.
Limited data exist about the prognostic significance of new-onset atrial fibrillation (AF) after contemporary primary percutaneous coronary intervention (pPCI). The objective of this study was to identify the incidence and predictors of new-onset AF and associated adverse 30-day outcomes in AF patients who underwent pPCI. ⋯ New-onset AF after pPCI is associated with adverse 30-day outcomes. Accurate prediction of AF after pPCI might help deciding a more aggressive treatment approach aimed at preventing the adverse prognosis of these patients.
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Coronary artery disease · Jan 2012
Elevated red cell distribution width level predicts worse postinterventional thrombolysis in myocardial infarction flow reflecting abnormal reperfusion in acute myocardial infarction treated with a primary coronary intervention.
Red cell distribution width (RDW), a measure of circulating erythrocyte size heterogeneity, is an established predictor of long-term prognosis and also all-cause mortality in a variety of cardiovascular settings. The correlation of RDW and reperfusion in acute myocardial infarction (AMI) has not been reported. Herein, we aimed to demonstrate the impact of an elevated RDW level on the postinterventional thrombolysis in myocardial infarction (TIMI) flow in AMI patients. ⋯ An elevated RDW level on admission is associated with worse reperfusion in AMI treated with a primary coronary intervention, which could be one of the factors that may contribute toward the association between elevated RDW and long-term adverse cardiovascular outcomes and mortality.