Coronary artery disease
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Coronary artery disease · May 2016
The relationship between admission monocyte HDL-C ratio with short-term and long-term mortality among STEMI patients treated with successful primary PCI.
Monocyte to HDL-C ratio (MHR) represents a simple assessment method for inflammatory status. The aim of the present study was to investigate whether MHR may be of short-term and long-term prognostic value in ST-elevation myocardial infarction (STEMI) patients who have undergone a primary percutaneous coronary intervention (PCI). ⋯ The results of this study have indicated that admission MHR is associated independently and significantly with short-term and long-term mortality in STEMI patients who undergo successful primary PCI.
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Coronary artery disease · May 2016
Comparative StudyFactors influencing platelet reactivity in patients undergoing coronary artery bypass surgery.
Because coronary artery bypass graft (CABG) surgery is associated with a high turnover of platelets, assessment of platelet function should enable assessment of the effect of young (RNA-containing) platelets on platelet reactivity. This study was designed to assess platelet reactivity 1 day after CABG in patients treated previously with clopidogrel or ticagrelor. ⋯ Young platelets were more reactive and, consistent with the irreversible binding of clopidogrel to P2Y12, this effect was more pronounced after treatment with clopidogrel. The reversible binding of ticagrelor to the platelet P2Y12 receptor may be advantageous in patients with a high platelet turnover.