Coronary artery disease
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Coronary artery disease · Jan 2012
Elevated red cell distribution width level predicts worse postinterventional thrombolysis in myocardial infarction flow reflecting abnormal reperfusion in acute myocardial infarction treated with a primary coronary intervention.
Red cell distribution width (RDW), a measure of circulating erythrocyte size heterogeneity, is an established predictor of long-term prognosis and also all-cause mortality in a variety of cardiovascular settings. The correlation of RDW and reperfusion in acute myocardial infarction (AMI) has not been reported. Herein, we aimed to demonstrate the impact of an elevated RDW level on the postinterventional thrombolysis in myocardial infarction (TIMI) flow in AMI patients. ⋯ An elevated RDW level on admission is associated with worse reperfusion in AMI treated with a primary coronary intervention, which could be one of the factors that may contribute toward the association between elevated RDW and long-term adverse cardiovascular outcomes and mortality.
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Coronary artery disease · Dec 2011
Comparative StudyThirty-day outcome after transcatheter aortic valve implantation compared with surgical valve replacement in patients with high-risk aortic stenosis: a matched comparison.
Transcatheter aortic valve implantation (TAVI) has become a therapeutic alternative to surgery for the treatment of severe aortic stenosis in high-surgical risk patients. The aim of this study was to compare 30-day mortality of high-risk patients treated by TAVI versus surgical aortic valve replacement. ⋯ In high-surgical risk patients, TAVI can be performed at a mortality risk comparable with conventional surgery with a reduced length of post interventional intensive care unit stay and less need for dialysis.
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Coronary artery disease · Dec 2011
Comparative StudyComparison of inflammatory markers for the prediction of neointimal hyperplasia after drug-eluting stent implantation.
We compared the relationship between inflammatory markers and neointimal hyperplasia (NIH) after drug-eluting stent (DES) implantation. ⋯ This prospective intravascular ultrasound study showed the inflammatory response after PCI, as measured by hs-CRP levels, but not the baseline hs-CRP level, predict NIH after DES implantation. Neither a change in the IL-6 nor MMP-9 levels at any stage after PCI reflected NIH.
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Coronary artery disease · Dec 2011
Long-term coronary artery graft patency as evaluated by 64-slice coronary computed tomographic angiography.
Coronary artery bypass graft (CABG) surgery has been a mainstream surgical procedure for coronary artery disease for the past three decades. 64-Slice coronary computed tomographic angiography (CCTA) has been established as an accurate alternative to invasive coronary artery angiography for postoperative evaluation of bypass grafts. The goal for this study was to utilize CCTA to evaluate long-term graft patency for various graft types as well as their targets. ⋯ In conclusion, this study confirms the practicality of using CCTA in a community setting to study bypass graft patency. The choice of graft is significant for long-term patency. This study raises doubt on the long-term fate of RA and further studies should be conducted to better evaluate their outcomes.
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Coronary artery disease · Aug 2011
Necrotic core and thin cap fibrous atheroma distribution in native coronary artery lesion-containing segments: a virtual histology intravascular ultrasound study.
The aim of this study was to assess the longitudinal topographical relationships between minimal luminal area (MLA) sites and plaques with the most vulnerable characteristics using radiofrequency-based virtual histology intravascular ultrasound analysis. ⋯ In coronary artery segments with intermediate-to-severe stenosis, plaques containing maxNC are mostly located away from the MLA site and more often comprise virtual histology-characterized thin cap fibrous atheroma. Such data may carry practical implications for coronary revascularization procedures.