Journal of nephrology
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Journal of nephrology · Mar 2013
Comparative StudyStent-grafts versus angioplasty and/or bare metal stents for failing arteriovenous grafts: a cross-over longitudinal study.
A well-established method to preserve failing synthetic arteriovenous grafts (AVGs) dialysis accesses is percutaneous transluminal angioplasty (PTA). Nevertheless, the one-year primary patency rate following PTA is approximately 25%. This study was designed to compare the angiographic and clinical outcomes following stent-graft insertion versus angioplasty and/or bare metal stenting (BMS) of recurrently failing AVGs, because of anastomotic and/or venous outflow stenoses. ⋯ Stent-graft placement significantly improves primary patency of anastomotic and venous outflow stenoses in recurrently failing prosthetic arteriovenous grafts.
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Journal of nephrology · Mar 2013
Quantification of experimental acute kidney injury by computer-assisted imaging of lectin phytohemagglutinin E.
Acute kidney injury (AKI) in sepsis accompanied by functional impairment regularly lacks histologic pathology to a similar extent. Moderately reproducible - semi-quantitative - scoring systems still remain the method of choice to quantify the extent of experimental AKI. Our aim was to establish a rather simple, fast, and reproducible staining protocol to quantify loss of brush border (BB) in septic AKI. ⋯ Our results demonstrate that PHA-E lectin staining followed by planimetric quantification is a reliable tool to analyze loss of BB during experimental AKI.