Journal of nephrology
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Journal of nephrology · Feb 2015
Randomized Controlled TrialDiuretic response to colloid and crystalloid fluid loading in critically ill patients.
In the critically ill patient, fluid loading is commonly done to stabilise hemodynamics and increase diuresis, whereas the absence of diuresis may predispose to harmful overloading. The goal of the current study was to evaluate the diuretic response and determinants thereof upon crystalloid and colloid fluid loading. ⋯ In critically ill patients with clinical hypovolemia, diuresis increases more during saline than colloid fluid loading, only partly dependent of a fall in plasma COP.
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Journal of nephrology · Feb 2015
Review Meta AnalysisUrine interleukin-18 in prediction of acute kidney injury: a systemic review and meta-analysis.
Interleukin-18 (IL-18) mediates ischemic acute tubular necrosis; it has been proved as a rapid, reliable, and affordable test marker for the early detection of acute kidney injury (AKI), but its predictive accuracy varies greatly. ⋯ Urine IL-18 holds promise as a biomarker in the prediction of AKI but has only moderate diagnostic value.
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Journal of nephrology · Feb 2015
Pericarditis in uremic patients: serum albumin and size of pericardial effusion predict drainage necessity.
Pericardial effusion in uremic patients (UPE) was first described by R. Bright in 1836. It is generally agreed that patients require emergency pericardial drainage when tamponade signs are present, but in patients with no tamponade the optimal timing for drainage remains unclear. ⋯ In this first study reporting UPE drainage risk factors, all large UPE required drainage even when extra-renal epuration intensification or medical treatment were tried. This suggests that large UPE should be drained without delay. For small and moderate UPE, size of effusion on echocardiography does not predict drainage requirement but serum albumin level does.