Journal of nephrology
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Journal of nephrology · Apr 2015
Randomized Controlled Trial Multicenter StudyAcute kidney injury after cardiac surgery: is minocycline protective?
Acute kidney injury (AKI) after cardiac bypass surgery (CABG) is common and carries a significant association with morbidity and mortality. Since minocycline therapy attenuates kidney injury in animal models of AKI, we tested its effects in patients undergoing CABG. ⋯ Minocycline did not protect against AKI post-CABG.