Journal of nephrology
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Journal of nephrology · Dec 2019
Randomized Controlled Trial Multicenter StudyTreatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study.
Metabolic acidosis is associated with accelerated progression of chronic kidney disease (CKD). Whether treatment of metabolic acidosis with sodium bicarbonate improves kidney and patient survival in CKD is unclear. ⋯ In persons with CKD 3-5 without advanced stages of chronic heart failure, treatment of metabolic acidosis with sodium bicarbonate is safe and improves kidney and patient survival.
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Journal of nephrology · Dec 2019
Observational StudyAcute kidney injury as an independent predictor of infection and malignancy: the NARA-AKI cohort study.
Acute kidney injury (AKI) is associated with higher mortality and cardiovascular events. However, association between AKI and non-cardiac events such as infection or malignancy is largely unknown. ⋯ AKI was significantly associated with hospitalization for infection and development of malignancy during long-term follow-up. Those with AKI might be in persistent immunosuppressed state.