Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Jan 1996
Comparative StudyEffects of estradiol and interaction with progesterone or oxytocin on term human myometrial contractile activity.
To investigate the effects of estradiol (E2) alone and in combination with progesterone or oxytocin on contractile activity of term human myometrium in vitro. ⋯ These data suggest that E2 had both stimulatory and inhibitory effects on term human myometrial contractility and that E2 altered the myometrial response to progesterone and oxytocin mainly by decreasing tonus.