Acta obstetricia et gynecologica Scandinavica
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Acta Obstet Gynecol Scand · Aug 2000
Historical ArticleSwedish maternal mortality in the 19th century by different definitions: previous stillbirths but not multiparity risk factor for maternal death.
The high maternal mortality levels in today's developing countries were also found throughout the history of currently affluent countries. The parish information system in Sweden offers unique possibilities for research in historical cohorts. Furthermore, vital events surveillance systems are scarce in today's developing countries. ⋯ In conclusion, this study shows that the mother's reproductive history was the most important risk factor measured for all definitions of maternal death. Grand multiparity did not increase the risk of maternal death. Maternal mortality ratio varied threefold in the study population, depending on the definition used. The high mortality ratios found in this study, only declining by the end of the century, should be interpreted as a general condition of the society since no significant differences could be perceived regarding social class, while unmarried women were more at risk.
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Acta Obstet Gynecol Scand · Aug 2000
Birth outcomes in pregnant women treated with low-molecular-weight heparin.
Pregnancy and puerperium are associated with an increased risk of venous thromboembolism. Low-molecular-weight heparin is the anticoagulant of choice in pregnant women because, unlike warfarin, it does not cross the placenta. However, there are limited data on the risk of adverse birth outcomes following use of low-molecular-weight heparin in pregnancy. ⋯ We have provided additional evidence of the safety of low-molecular-weight heparin use in pregnancy.
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Acta Obstet Gynecol Scand · Aug 2000
Clinical TrialTermination of second trimester pregnancy with mifepristone and gemeprost. The clinical experience of 197 consecutive cases.
Earlier controlled clinical trials have demonstrated that combined treatment with the antiprogestagen, mifepristone and a suitable prostaglandin reduce the induction to abortion time in second trimester abortion. The aim of this study was to describe the results of the 197 consecutive second trimester terminations performed in routine clinical practice at our Department from 1996 to 1998. ⋯ The study confirms the efficacy and safety of mifepristone, together with gemeprost, for termination of second trimester pregnancy when routinely used in the clinic.