Acta oto-laryngologica
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The olfactory event-related potential (OERP) method provides a means of objectively assessing olfactory function. However, further validation is needed before OERPs can be routinely applied in clinical assessment of olfactory dysfunction. ⋯ The OERP amplitudes increased and the latencies shortened with increasing stimulus concentration. Furthermore, a difference between the groups was found, with higher OERP amplitudes and shorter latencies in healthy subjects compared with patients.
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Acta oto-laryngologica · Sep 2008
Efficacy of total intravenous anesthesia without intubation for laryngeal framework surgery.
Total intravenous anesthesia (TIVA) without intubation has the advantages of both conventional general anesthesia and local anesthesia. It is useful in laryngeal framework surgery because intraoperative voice monitoring while the patient remains awake is required. ⋯ The BIS value during continued administration of propofol was around 60, but exceeded 90 in all patients within 233.6 +/- 64.5 s after cessation. They clearly remembered the conversation they had with us during surgery.
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Acta oto-laryngologica · Aug 2008
Randomized Controlled TrialIntratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial.
Intratympanic application of gentamicin is a relatively safe and efficient treatment for the reduction of complaints of vertigo attacks associated with Menière's disease. The treatment also reduces the severity of the perceived aural fullness. ⋯ Gentamicin treatment resulted in a significant reduction of the score for vertigo complaints and the score for perceived aural fullness. A small increase in hearing loss (average 8 dB) was measured in the gentamicin group.
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Acta oto-laryngologica · Jul 2008
Randomized Controlled Trial Comparative StudyNitrous oxide for applying local anesthesia in nasal operations: a randomized placebo-controlled single-blinded study.
In our study setting nitrous oxide (N(2)O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N(2)O in application of local anesthesia in nasal surgery. ⋯ The N(2)O inhalation was easy to perform and well tolerated. The N(2)O inhalation before applying local anesthesia for nasal operations did not show any significant additional benefit in reducing pain or discomfort.
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Acta oto-laryngologica · Jun 2008
Evidence for increased NADPH-diaphorase-positive neurons in the central auditory system of the aged rat.
The age-related increase in the production of nitric oxide (NO) suggests that this increase was related to neuron aging. Additional studies may provide information regarding aging-related changes in the central auditory system. ⋯ The number of NADPH-d-positive neurons in the inferior colliculus was significantly increased in aged rats (p<0.05), whereas the area of NADPH-d-positive neurons in all areas did not differ significantly between aged and younger rats (p>0.05). The staining densities of NADPH-d-positive neurons in the inferior colliculus, the auditory cortex, and the visual cortex were significantly greater in aged compared with younger rats (p<0.05).