The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
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J. Heart Lung Transplant. · Feb 2007
A practical approach to clinical lung transplantation from a Maastricht Category III donor with cardiac death.
Although donation after cardiac death (DCD) has the potential to provide a novel source of organs for lung transplantation, even in a controlled DCD situation such as a Maastricht Category III donor (withdrawal of treatment), the limited time frame available after the declaration of death to initiate procurement and preservation remains challenging. Indeed, no publication has detailed the exact time frames and technique applicable for successful Maastricht Category III DCD lung procurement. In this patient report, withdrawal of life-support treatment and death certification was performed in the intensive care unit and the lungs were procured in an operating room 49 minutes after cardiac arrest and successfully transplanted (cold ischemia time <6 hours) into a severely ill recipient with primary pulmonary hypertension.
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J. Heart Lung Transplant. · Feb 2007
Comparative StudyLong-term health-related quality of life after lung transplantation: different predictors for different dimensions.
Lung transplantation has proven to be an effective treatment option for patients with end-stage lung disease with profound effects on both survival and health-related quality of life (HRQL). Generally, studies have reported improved HRQL after lung transplantation. When assessing HRQL, physical, psychologic or social dimensions are usually included. However, it is unclear what predicts outcome, to what extent, and whether there are differences in predictors between dimensions of HRQL. Knowledge about these predictors may be useful when making choices regarding therapy. The research question in the present study was: What are the predicting variables of physical and psychologic dimensions of HRQL, and do they differ? ⋯ Several variables were identified that predicted HRQL after lung transplantation. These variables differed between the physical and psychologic dimensions. The presence of BOS was a predictor for both dimensions. The present findings may be helpful when choosing or developing interventions aimed at improving HRQL after lung transplantation.
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J. Heart Lung Transplant. · Feb 2007
Parenting stress and parental post-traumatic stress disorder in families after pediatric heart transplantation.
There has been little research on the stress experienced by parents of children who have undergone heart transplantation. ⋯ Illness-related parenting stress and post-traumatic stress symptoms are significant concerns among parents of pediatric heart transplant patients. Parents' psychologic functioning post-transplant should be routinely assessed and addressed by transplant teams.
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J. Heart Lung Transplant. · Feb 2007
Pre-transplant mechanical ventilation increases short-term morbidity and mortality in pediatric patients with cystic fibrosis.
Patients with cystic fibrosis (CF) who are listed for lung transplantation may require mechanical ventilatory support before transplant. Although CF is a risk factor for poor outcomes in adults, no data currently exist pertaining to pre-transplant ventilatory support in children with CF. ⋯ This is the first report in pediatric patients with CF demonstrating that mechanical ventilation before lung transplant is a predictor of poor short-term outcomes, including 1-year-survival, after transplant. Length of pre-transplant ventilatory support does not appear to impact outcomes.
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J. Heart Lung Transplant. · Feb 2007
Case ReportsBilateral lung transplantation from a donor with fume poisoning.
Organ transplantation is limited by a worldwide organ scarcity. Heart and lung transplantation are particularly affected by this limitation. Consequently, there is increasing interest in transplantation of organs from marginal donors. We report a patient who underwent successful bilateral lung transplantation from a donor with fume poisoning and subsequent resuscitation.