Journal of neuroimaging : official journal of the American Society of Neuroimaging
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The Reversible Splenial Lesion Syndrome represents a distinct clinicoradiological syndrome, associated with several disorders, including infection, high altitude cerebral edema, antiepileptic drug withdrawal, and severe metabolic disturbances (hypoglycemia and hypernatremia). Clinical presentation is nonspecific, most frequently as an encephalopathy or encephalitis. ⋯ Findings on diffusion-weighted imaging are consistent with cytotoxic edema except for high-altitude cerebral edema, where vasogenic edema is present. Resolution after weeks or months is the rule.
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Botulinum toxin (BTX) treatment can relieve focal arm spasticity after stroke, presumably through dynamic changes at multiple levels of the motor system, including the cerebral cortex. However, the neuroanatomical correlate of BTX spasticity relief is not known and should be reflected in changes of cortical activation during motor tasks assessed using repeated functional magnetic resonance imaging (fMRI). ⋯ This small study suggests that structures outside the classical motor system, such as the posterior cingulate/precuneus region, may be associated with the relief of poststroke arm spasticity.
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Assess the safety and efficacy of the continuous transcranial duplex Doppler (TCDD) monitoring of middle cerebral artery (MCA) (M1-2) occlusion in acute ischemic stroke (IS) patients and compare TCDD to intra-arterial thrombolysis (IAT) and intravenous thrombolysis (IVT). ⋯ Continual TCDD monitoring might be safe and potentially beneficial in treatment of MCA occlusion.
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Double Inversion Recovery Magnetic Resonance Imaging (DIR) consists of two adiabatic non-selective inversion pulses applied before a Turbo Spin Echo (TSE) sequence, in order to suppress the signal from two tissues with different longitudinal relaxation times T(1) simultaneously. In the brain, DIR is used to selectively image the gray matter (GM) by nulling the signal from white matter (WM) and cerebrospinal fluid (CSF). The main limitation of the technique remains the intrinsic low SNR due to the specific preparation of the longitudinal magnetization. The recent availability of high field magnets operating at 7 T for human imaging offers the advantage of higher SNR. This study shows the feasibility of brain Double Inversion Recovery Magnetic Resonance Imaging (DIR-MRI) at 7 T in vivo in healthy volunteers. ⋯ DIR is feasible at 7 T despite the problems associated with B(1) in-homogeneity.