Journal of neuroimaging : official journal of the American Society of Neuroimaging
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To evaluate the safety of thrombolysis with rt-PA in acute ischemic strokes during a 12-hour time window using an ultrafast MR protocol. ⋯ Our results demonstrated the safety of thrombolysis with rt-PA in selected stroke patients within a 12-hour time window using an ultrafast MR protocol.
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Major depressive disorder (MDD) presents with extensive clinical heterogeneity. In particular, overlap with anxiety symptoms is common during depressive episodes and as a comorbid disorder. The aim of this study was to test for morphological brain differences between patients having a history of recurrent MDD with, and without, anxiety symptoms (MDD+A and MDD-A). ⋯ Regional volume differences in patients are consistent with altered neuronal or glial microstructure. The temporolateral cortical differences distinguishing the 2 MDD groups suggest neurobiological differences related to the expression of anxiety symptoms in depression and provide further rationale for considering these groups independently for therapeutic outcomes studies.
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Susceptibility-Weighted Imaging (SWI) is a relatively new magnetic resonance imaging (MRI) sequence relying on susceptibility differences between adjacent tissues to produce an image. It is extremely sensitive for detection of blood products (hemosiderin, ferritin), deoxygenated blood, calcium, iron, and small vein depiction. Little information is available in the literature to describe common findings seen using this imaging sequence. This article is an comprehensive review of appearances across the spectrum of brain pathology encountered in routine clinical practice. ⋯ SWI is an extremely useful adjunct to current MRI sequences of the brain and is advocated for inclusion into routine Neuroimaging protocols.
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We describe the essential diffusion tensor imaging (DTI) findings of right cerebral hemisphere infarctions and study whether the DTI parameters and neurological status differ in patients with visible wallerian degeneration (WD) or small hemorrhagic transformation (HT) in the chronic stage. ⋯ DTI reveals the changes after infarction in the lesion site and elsewhere. The patients with visible WD or HT have more changes in the DTI parameters and worse outcome scores.
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Susceptibility-weighted imaging (SWI) is a relatively new MRI sequence relying on susceptibility differences between adjacent tissues to produce an image. It is extremely sensitive for detection of blood products (hemosiderin, ferritin), deoxygenated blood, calcium, iron, and small vein depiction. ⋯ The potential of this new sequence can be reviewed in comprehensive article "Susceptibility-Weighted Imaging of the Brain: Current Utility and Potential Applications" available online. SWI is an extremely useful adjunct to current MRI sequences of the brain and is advocated for inclusion into routine Neuroimaging protocols.