Journal of neuroimaging : official journal of the American Society of Neuroimaging
-
Randomized Controlled Trial Multicenter Study
Derivation and evaluation of thresholds for core and tissue at risk of infarction using CT perfusion.
Computed tomography perfusion provides information on tissue viability according to proposed thresholds. We evaluated thresholds for ischemic core and tissue at risk and subsequently tested their accuracy in independent datasets. ⋯ Time-based perfusion thresholds perform well as predictors of tissue at risk of infarction with DT the best predictor. Relative CBF was the best predictor of ischemic core. Evaluation in larger populations is needed to confirm the performance of tissue viability thresholds.
-
Case Reports
Early experience with low contrast imaging (LCI) technology during neuroendovascular interventional procedures.
Early recognition of complications during intracranial neuroendovascular interventions is important for medical decision making and prompts administration of life-saving treatments. Low contrast imaging (LCI) provides computed tomographic (CT)-like images of anatomical brain structures, capable of detecting hydrocephalus and intracranial hemorrhage complications. We present our early experience with LCI using the Toshiba Infinix-i biplane angiographic suite during neurointerventional cases, including acute stroke interventions, aneurysm embolization, and subarachnoid hemorrhage management. ⋯ LCI is a promising tool in the arsenal of a neuroendovascular interventionist, especially when a complication is suspected during an intervention, potentially obviating the need for immediate transfer of the patient to a conventional CT scanner. Further studies comparing LCI with conventional noncontrast CT imaging are necessary.
-
The events leading up to the development of new multiple sclerosis (MS) lesions on conventional imaging are unknown. The purpose of this study is to use diffusion tensor imaging (DTI) to investigate prelesional changes in MS to better understand the pathological changes that lead to lesion development. ⋯ A significant change in diffusion measures can be seen prior to gadolinium enhancement. Changes in TD drove changes in FA and MD, providing evidence for impaired myelin integrity prior to gadolinium enhancement. DTI may be a sensitive measure for early detection of inflammatory disease activity in MS.
-
An organized hematoma shows a heterogeneous signal intensity on T1-and T2-weighted images on MR imaging, reflecting variable stages of hemorrhage. Although rather nonspecific, precontrast CT images of an organized hematoma demonstrate inhomogeneous hyperdense mass with or without calcification. ⋯ Computed tomography and magnetic resonance imaging findings of the organized hematoma are shown and discussed. We believe that recognition of the characteristic imaging findings of the organized hematoma as well as consideration of the history of surgery or anticoagulation treatment assists in its correct diagnosis enabling an inappropriate surgery to be avoided.
-
To explore the safety and opportunity of the "waffle-cone" technique for the treatment of intracranial aneurysm. ⋯ The "waffle-cone" technique is a safe, simple and alternative for the complex, wide-necked bifurcation aneurysms with acute angles between the parent artery and distal vessels. Long-term following-up results are needed to evaluate the efficacy of this technique.