Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Comparative Study Observational Study
Effect of SOHAM meditation on human brain: a voxel-based morphometry study.
The anatomical correlates of long-term meditators involved in practice of "SOHAM" meditation have been studied using voxel-based morphometry (VBM). The VBM analysis indicates significantly higher gray matter density in brain stem, ventral pallidum, and supplementary motor area in the meditators as compared with age-matched nonmeditators. The observed changes in brain structure are compared with other forms of meditation.
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Integration of functional connectivity analysis based on resting-state functional Magnetic Resonance Imaging (fMRI) and structural connectivity analysis based on Diffusion-Weighted Imaging (DWI) has shown great potential to improve understanding of the neural networks in the human brain. However, there are sensitivity and specificity-related interpretation issues that must be addressed. ⋯ This fMRI/DWI integration study suggests that functional connectivity analysis might be a more sensitive and robust approach in understanding the connectivity between cortical regions, and can be used to improve DWI-based structural connectivity analysis.
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Comparative Study
Evaluating of small intracranial aneurysms by 64-detector CT Angiography: a comparison with 3-dimensional rotation DSA or surgical findings.
The diagnostic performance of 64-detector computed tomographic angiography (CTA) for detection of small intracranial aneurysms (SIAs) was evaluated. ⋯ The diagnostic performance of 64-detector CTA did not improve much compared with 16-detector CTA for detecting SIAs, especially for very small aneurysms. VR-RDSA is still necessary for patients with a history of subarachnoid hemorrhage if the CTA findings are negative.
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This study aimed to identify predictors of acute mortality after intracerebral hemorrhage (ICH), including voxel-wise analysis of hematoma location. ⋯ For patients with lobar ICH, acute mortality is related to both hematoma size and location, with findings potentially useful for therapeutic decision making. The current findings also underscore differences between the syndromes of acute deep and lobar ICH.
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Vertebral artery dissection (VAD) is one of the most important etiologies in young stroke patients. VAD causes ischemic stroke by embolism and transcranial Doppler (TCD) monitoring can detect microemboli originating from the dissection point as high intensity transient signals (HITS). We developed a simple but novel method of TCD monitoring at the vertebrobasilar junction in VAD patients. ⋯ We successfully detected HITS at the vertebrobasilar junction in VAD patients, which may lead not only to an appropriate choice of antithrombotic drugs but also to individual evaluation of early risk of ischemic recurrence.