Journal of neuroimaging : official journal of the American Society of Neuroimaging
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To determine if a voxel-wise "co-analysis" of structural and diffusion tensor magnetic resonance imaging (MRI) together reveals additional brain regions affected in mild cognitive impairment (MCI) and Alzheimer's disease (AD) than voxel-wise analysis of the individual MRI modalities alone. ⋯ These results suggest that in corpus callosum and temporal regions macro- and microstructural variations in MCI can be congruent, providing potentially new insight into the mechanisms of brain tissue degeneration.
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Arterial spin labeling (ASL) MRI provides information on tissue perfusion by consecutive readout of labeled blood captured in arteries or the microvasculature without using contrast agents. ⋯ The use of ASL with multiple TI allows the contrast-free assessment of hemodynamic impairment in ischemic stroke patients. Quantitative ASL perfusion analysis reliably demonstrates areas of delayed BAT and reduced CBF matching findings of DSC.
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Clinical Trial
Increased common carotid artery wall thickness is associated with rapid progression of asymptomatic carotid stenosis.
This study aimed to identify clinical and ultrasound imaging predictors of progression of carotid luminal narrowing in subjects with asymptomatic moderate internal carotid artery (ICA) stenosis. ⋯ Our results confirm the role of carotid wall thickening as a marker of atherosclerosis. Carotid IMT measurement should be considered to implement risk stratification in patients with asymptomatic carotid disease.
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Characterizing the morphologies of occluded artery segments may help elucidate the etiology of chronic intracranial artery occlusion. We acquired high-resolution MRI (HR-MRI) of the middle cerebral artery (MCA) in patients with chronic unilateral MCA occlusion and evaluated the MRI and clinical findings. ⋯ HR-MRI can characterize the morphology of pathologic segments of chronic unilateral MCA occlusions in vivo. In chronic MCA occlusion, morphological analysis using HR-MRI may enhance the effort to assess the etiology in company with the angiographic finding.
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This study was designed to evaluate various magnetic resonance imaging (MRI) criteria for cavernous sinus (CS) invasion in preoperative evaluation of pituitary macroadenoma. ⋯ MRI criteria may be helpful in evaluating the presence of CS invasion in pituitary macroadenoma.