Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Clinical Trial
Increased common carotid artery wall thickness is associated with rapid progression of asymptomatic carotid stenosis.
This study aimed to identify clinical and ultrasound imaging predictors of progression of carotid luminal narrowing in subjects with asymptomatic moderate internal carotid artery (ICA) stenosis. ⋯ Our results confirm the role of carotid wall thickening as a marker of atherosclerosis. Carotid IMT measurement should be considered to implement risk stratification in patients with asymptomatic carotid disease.
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Characterizing the morphologies of occluded artery segments may help elucidate the etiology of chronic intracranial artery occlusion. We acquired high-resolution MRI (HR-MRI) of the middle cerebral artery (MCA) in patients with chronic unilateral MCA occlusion and evaluated the MRI and clinical findings. ⋯ HR-MRI can characterize the morphology of pathologic segments of chronic unilateral MCA occlusions in vivo. In chronic MCA occlusion, morphological analysis using HR-MRI may enhance the effort to assess the etiology in company with the angiographic finding.
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Arterial spin labeling (ASL) MRI provides information on tissue perfusion by consecutive readout of labeled blood captured in arteries or the microvasculature without using contrast agents. ⋯ The use of ASL with multiple TI allows the contrast-free assessment of hemodynamic impairment in ischemic stroke patients. Quantitative ASL perfusion analysis reliably demonstrates areas of delayed BAT and reduced CBF matching findings of DSC.
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Controlled Clinical Trial
Jugular valve incompetence in transient global amnesia. A problem revisited.
Previous studies have suggested that transient global amnesia (TGA) may be provoked by cerebral venous congestion due to a reflux during Valsalva maneuver (VM) caused by internal jugular venous valve incompetence (IJVVI). We investigated the hemodynamic consequences of postural changes on IJVVI and on intracranial veins in patients with TGA and control subjects. ⋯ Consistent with results of other groups, we found a significantly higher rate of IJVVI in TGA patients compared to controls. However, we found no differences of intracranial venous circulation between groups nor an effect of body position. This sheds doubt on the assumption of a causative effect of IJVVI in TGA.
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This study was designed to evaluate various magnetic resonance imaging (MRI) criteria for cavernous sinus (CS) invasion in preoperative evaluation of pituitary macroadenoma. ⋯ MRI criteria may be helpful in evaluating the presence of CS invasion in pituitary macroadenoma.