Journal of neuroimaging : official journal of the American Society of Neuroimaging
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An effort to define and validate a Harmonized Protocol for standard hippocampal segmentation is being carried out. We wished to estimate the effect of magnetic resonance image (MRI) spatial orientation on manual hippocampal segmentations to define optimal standard orientation of MRIs for hippocampal volumetry. ⋯ These data show that AC-PC orientation is slightly more reliable for manual segmentations, possibly due to better visualization of the cerebrospinal fluid spaces separating hippocampal head and amygdala. A Delphi panel of experts has used these data to decide on the optimal orientation for a Harmonized Protocol for hippocampal segmentation.
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Clinical Trial
Increased common carotid artery wall thickness is associated with rapid progression of asymptomatic carotid stenosis.
This study aimed to identify clinical and ultrasound imaging predictors of progression of carotid luminal narrowing in subjects with asymptomatic moderate internal carotid artery (ICA) stenosis. ⋯ Our results confirm the role of carotid wall thickening as a marker of atherosclerosis. Carotid IMT measurement should be considered to implement risk stratification in patients with asymptomatic carotid disease.
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This study was designed to evaluate various magnetic resonance imaging (MRI) criteria for cavernous sinus (CS) invasion in preoperative evaluation of pituitary macroadenoma. ⋯ MRI criteria may be helpful in evaluating the presence of CS invasion in pituitary macroadenoma.
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This study was designed to evaluate various magnetic resonance imaging (MRI) criteria for cavernous sinus (CS) invasion in preoperative evaluation of pituitary macroadenoma. ⋯ MRI criteria may be helpful in evaluating the presence of CS invasion in pituitary macroadenoma.
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Controlled Clinical Trial
Jugular valve incompetence in transient global amnesia. A problem revisited.
Previous studies have suggested that transient global amnesia (TGA) may be provoked by cerebral venous congestion due to a reflux during Valsalva maneuver (VM) caused by internal jugular venous valve incompetence (IJVVI). We investigated the hemodynamic consequences of postural changes on IJVVI and on intracranial veins in patients with TGA and control subjects. ⋯ Consistent with results of other groups, we found a significantly higher rate of IJVVI in TGA patients compared to controls. However, we found no differences of intracranial venous circulation between groups nor an effect of body position. This sheds doubt on the assumption of a causative effect of IJVVI in TGA.