Journal of neuroimaging : official journal of the American Society of Neuroimaging
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Source-based morphometry(SBM) has been used in multicenter studies pooling magnetic resonance imaging data across different scanners to advance the reproducibility of neuroscience research. In the present study, we developed an analysis strategy for Scanner-Specific Detection (SS-Detect) of SBPs in multiscanner studies, and evaluated its performance relative to a conventional strategy. ⋯ SS-Detect outperformed the conventional strategy and can be considered advantageous when SBM is applied to a multiscanner study.
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Vestibular symptoms after concussion are common and associated with protracted recovery. The purpose of this study is to define resting-state functional MRI (rs-fMRI) brain connectivity alterations in patients with postconcussion vestibular dysfunction (PCVD) and correlations between rs-fMRI connectivity and symptoms provoked during Vestibular/Ocular-Motor Screening (VOMS) assessment. ⋯ Altered rs-fMRI brain connectivity with increased connectivity of visual input, multisensory processing, and spatial memory in PCVD is correlative with clinical derivative VOMS scores, suggesting maladaptive brain plasticity underlying vestibular symptomatology.
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The comparative detection rates of deep gray matter (GM) multiple sclerosis (MS) lesions using double inversion recovery (DIR) and fluid-attenuated inversion-recovery (FLAIR) on 3T MR imaging remain unknown. We aimed to assess the detectability of cortical and deep GM MS lesions using DIR and FLAIR on 3T clinical exams and evaluate the relationship between deep GM lesions and brain atrophy. ⋯ Deep GM MS lesions can be detected using routine clinical brain MRI including DIR and FLAIR at 3T. Future studies to optimize these sequences may improve the detection rates of cortical and deep GM lesions. The presence of GM lesions showed weak correlation with GM atrophy.