Acta psychiatrica Scandinavica
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Acta Psychiatr Scand · Jun 2009
ReviewHow to read and understand and use systematic reviews and meta-analyses.
Systematic reviews and meta-analyses are increasingly frequently used in the evaluation of medical treatments. This review explains the principles of the methodology, significance and limitations of systematic reviews. ⋯ Due to the enormous amount of scientific information published every year, systematic reviews and meta-analyses have become indispensable methods for the evaluation of medical treatments.
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Acta Psychiatr Scand · Jun 2009
ReviewEarly intervention in patients at ultra high risk of psychosis: benefits and risks.
Prediction of transition to psychosis in the prodromal phase of schizophrenia has raised interest in intervention prior to the onset of frank psychosis. The aim of this review was to examine whether interventions in the prodromal phase have a favourable benefit/risk ratio. ⋯ At the present time, the data concerning the benefits and risks do not justify prodromal intervention as standard clinical practice.