Acta psychiatrica Scandinavica
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Acta Psychiatr Scand · Jun 2015
Randomized Controlled TrialMaintained superiority of chronotherapeutics vs. exercise in a 20-week randomized follow-up trial in major depression.
To investigate the long-term antidepressant effect of a chronotherapeutic intervention. ⋯ In this clinical study patients continued to improve in the follow-up phase and obtained very high remission rates. This is the first study to show adjunct short-term wake therapy and long-term bright light therapy as an effective and feasible method to attain and maintain remission.