Enfermedades infecciosas y microbiología clínica
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Enferm. Infecc. Microbiol. Clin. · Sep 2020
Association of serum soluble Fas concentrations and mortality of septic patients.
Scarce data on Fas, one of the main receptors that activates the apoptosis extrinsic pathway, in septic patients exists. Higher blood soluble Fas (sFas) concentrations in non-survivor septic patients compared with survivors have been found in small studies; however, the association of blood sFas concentrations with mortality controlling for sepsis severity has not been stablished due to this small sample size in those studies. Thus, our main objective study was to determine whether an association between blood sFas concentrations and sepsis mortality controlling for sepsis severity exists. ⋯ That an association between blood sFas concentrations and sepsis mortality controlling for sepsis severity exists was our main new finding study.