The Journal of veterinary medical science
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Comparative Study
Effect of a 7.2% hypertonic saline solution infusion on arterial blood pressure, serum sodium concentration and osmotic pressure in normovolemic heifers.
The effects of an intravenous (i.v.) infusion of a small volume (5 ml/kg) or large volume (15 ml/kg) of hypertonic saline solution (HSS; 7.2%, 2,400 mOsmol/kg. H2O) and those of an i.v. infusion of 5 ml/kg isotonic saline solution (ISS; 300 mOsmol/kg. H2O) on plasma volume, arterial blood pressure, serum sodium concentrations and osmotic pressure were investigated in conscious heifers. ⋯ The 15 ml/kg HSS infusion induced a significant decrease in the partial pressure of oxygen at the t = 30 min compared to the t = 0 min values. On the basis of these findings, a small volume (5 ml/kg) HSS infusion can be rapidly and safely administered to cattle for expanding the plasma volume without inducing hypernatremia. A 5 ml/kg HSS infusion is thus recommended for the initial field resuscitation of cattle.