Journal of magnetic resonance imaging : JMRI
-
J Magn Reson Imaging · Jun 2005
Diffusion tensor fractional anisotropy of the normal-appearing seven segments of the corpus callosum in healthy adults and relapsing-remitting multiple sclerosis patients.
To investigate the utility of whole-brain diffusion tensor imaging (DTI) in elucidating the pathogenesis of multiple sclerosis (MS) using the normal-appearing white matter (NAWM) of the corpus callosum (CC) as a marker of occult disease activity. ⋯ The preliminary results are consistent with published histopathology and clinical studies on MS, but not with some published DTI reports. This study provides insights into the pathogenesis of MS, and the role played by compromised axonal integrity in this disease.
-
J Magn Reson Imaging · Jun 2005
Application of refocused steady-state free-precession methods at 1.5 and 3 T to in vivo high-resolution MRI of trabecular bone: simulations and experiments.
To evaluate the potential of fully-balanced steady-state free-precession (SSFP) sequences in in vivo high-resolution (HR) MRI of trabecular bone at field strengths of 1.5 and 3 T by simulation and experimental methods. ⋯ Single-acquisition SSFP (at 1.5 T) and multiple-acquisition SSFP (at 3 T) hold great potential for HR-MRI of trabecular bone.
-
J Magn Reson Imaging · Jun 2005
Quantitative perfusion measurements using pulsed arterial spin labeling: effects of large region-of-interest analysis.
To study arterial spin labeling (ASL) MRI techniques and to investigate various problematic issues that still hinder the accurate and robust quantitative analysis of ASL data. ⋯ Analysis of ASL data based on a large ROI may suffer from inaccuracies arising from a distribution of transit times, implying that averaging of ASL kinetic data over such regions should therefore be avoided. When possible, a PBP fit should be performed.
-
J Magn Reson Imaging · Jun 2005
Comparative StudyHigh-dose Gd-DTPA vs. Bis-Gd-mesoporphyrin for monitoring laser-induced tissue necrosis.
To compare Bis-Gd-mesoporphyrin (Bis-Gd-MP), a contrast agent with a reported high affinity to necrotic tissue, with high-dose gadopentate dimeglumin (Gd-DTPA) for defining laser-induced muscle and liver necrosis by contrast-enhanced (CE) MRI. ⋯ Bis-Gd-MP and Gd-DTPA are equally well suited for postinterventional lesion assessment in LITT.