Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Nov 2013
MRI-based prediction of pulsed high-intensity focused ultrasound effect on tissue transport in rabbit muscle.
To design an algorithm for optimizing pulsed high intensity focused ultrasound (p-HIFU) treatment parameters to maximize tissue transport while minimizing thermal necrosis based on MR image guidance. ⋯ Successful p-HIFU treatment was mainly correlated to tissue heating. Tissue transport properties following treatment success would result in improved contact between drug and targets in both time and space. MRI is the key to controlling treatment by means of thermometry and also monitoring efficacy by means of T2-weighted imaging.