Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Nov 2013
MRI-based prediction of pulsed high-intensity focused ultrasound effect on tissue transport in rabbit muscle.
To design an algorithm for optimizing pulsed high intensity focused ultrasound (p-HIFU) treatment parameters to maximize tissue transport while minimizing thermal necrosis based on MR image guidance. ⋯ Successful p-HIFU treatment was mainly correlated to tissue heating. Tissue transport properties following treatment success would result in improved contact between drug and targets in both time and space. MRI is the key to controlling treatment by means of thermometry and also monitoring efficacy by means of T2-weighted imaging.
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J Magn Reson Imaging · Nov 2013
Application of time-resolved angiography with stochastic trajectories (TWIST)-Dixon in dynamic contrast-enhanced (DCE) breast MRI.
To evaluate a magnetic resonance imaging (MRI) technique that integrates time-resolved angiography with stochastic trajectories (TWIST) view sharing and Dixon for a breast dynamic contrast-enhanced (DCE)-MRI application. ⋯ With proper parameters, TWIST-Dixon provides higher perceived SNR, more accurate fat suppression, and better overall image quality for breast DCE-MRI without sacrificing accuracy in the enhancement estimation.
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J Magn Reson Imaging · Nov 2013
ReviewDisclosing incidental findings in brain research: the rights of minors in decision-making.
MRI is used routinely in research with children to generate new knowledge about brain development. The detection of unexpected brain abnormalities (incidental findings; IFs) in these studies presents unique challenges. While key issues surrounding incidence and significance, duty of care, and burden of disclosure have been addressed substantially for adults, less empirical data and normative analyses exist for minors who participate in minimal risk research. ⋯ However, we found little discussion about the involvement of minors in decisions about disclosure of IFs in the brain, especially for IFs of low clinical significance. In response, we propose a framework for managing IFs that integrates practical considerations with explicit appreciation of rights along the continuum of maturity. This capacity-adjusted framework emphasizes the importance of involving competent minors and respecting their right to make decisions about disclosure.
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J Magn Reson Imaging · Nov 2013
Comparative StudyEffects of the use of multiple scanners and of scanner upgrade in longitudinal voxel-based morphometry studies.
To evaluate the effects of inter-scanner variability (bias) and of scanner upgrade on longitudinal changes in regional gray matter volume. ⋯ The results of our study indicate that, even with scanners of the exact same model, the use of different scanners at different time points significantly influences longitudinal morphometric results, and that scanner upgrade has effects comparable to those of using different scanners at different time points.
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J Magn Reson Imaging · Nov 2013
Accuracy of equilibrium magnetization mapping in sliced two-dimensional spoiled gradient-recalled echo pulse sequence with variable flip angle.
To evaluate the accuracy of an equilibrium magnetization (M0 ) map obtained using a two-dimensional (2D) spoiled gradient-recalled echo (SPGR) pulse sequence with variable flip angle (VFA). ⋯ M0 values calculated from 2D SPGR-VFA images are highly quantitative.