• J Magn Reson Imaging · Nov 2013

    Application of time-resolved angiography with stochastic trajectories (TWIST)-Dixon in dynamic contrast-enhanced (DCE) breast MRI.

    • Yuan Le, Hal Kipfer, Shadie Majidi, Stephanie Holz, Brian Dale, Christian Geppert, Randall Kroeker, and Chen Lin.
    • Department of Radiology and Imaging Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
    • J Magn Reson Imaging. 2013 Nov 1; 38 (5): 1033-42.

    PurposeTo evaluate a magnetic resonance imaging (MRI) technique that integrates time-resolved angiography with stochastic trajectories (TWIST) view sharing and Dixon for a breast dynamic contrast-enhanced (DCE)-MRI application.Materials And MethodsSimulation study: K-space data at six timepoints (1 pre-, 5 postcontrast) were generated by performing Fourier transform on a digital "phantom" with 3-9 mm enhancing lesions and three types of enhancement curves (persistent, plateau, washout). Images were reconstructed with and without TWIST. Clinical study: Six TWIST-Dixon image sets (one pre-, five postcontrast) were acquired in 18 patients on a 3T scanner, followed by one conventional image set. The last TWIST-Dixon and the conventional images were scored for seven criteria: perceived signal-to-noise ratio (P.SNR), visualization of anatomy, fat suppression (FS) accuracy, FS uniformity, ghosting artifact, edge ringing artifact, and overall image quality (IQ).ResultsSimulation study: With proper TWIST parameters (pA ≥33%, pB ≥50%), the enhancement underestimation was 5% or less for tumor size ≥5 mm. Clinical study: TWIST-Dixon images have significantly better scores in all criteria except for ghosting artifacts, where the difference was not significant.ConclusionWith proper parameters, TWIST-Dixon provides higher perceived SNR, more accurate fat suppression, and better overall image quality for breast DCE-MRI without sacrificing accuracy in the enhancement estimation.Copyright © 2013 Wiley Periodicals, Inc.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.