Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Feb 2014
Randomized Controlled Trial Multicenter StudyGadobutrol in the central nervous system at three doses: results from a phase II, randomized, multicenter trial.
To investigate the efficacy and safety of three doses of gadobutrol and determine the minimum effective dose for contrast-enhanced MRI of the central nervous system (CNS). ⋯ The 0.1 mmol/kg dose of gadobutrol was effective and well tolerated for contrast-enhanced MRI of the CNS.
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J Magn Reson Imaging · Feb 2014
Randomized Controlled Trial Comparative StudyComparison of three-dimensional pseudo-continuous arterial spin labeling perfusion imaging with gradient-echo and spin-echo dynamic susceptibility contrast MRI.
To compare the relative cerebral blood flow (CBF) obtained by pseudo-continuous arterial spin labeling sequence incorporated with volumetric fast spin-echo readout (3D-PCASL) with those by gradient-echo (GE) and spin-echo (SE) dynamic susceptibility contrast (DSC) MRI. ⋯ This study suggested that perfusion images obtained from 3D-PCASL exhibited significant correlations with DSC-MRI, with greater microvascular weighting like SE-DSC.