Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Dec 2015
Comparative StudyReproducibility of quantitative susceptibility mapping in the brain at two field strengths from two vendors.
To assess the reproducibility of brain quantitative susceptibility mapping (QSM) in healthy subjects and in patients with multiple sclerosis (MS) on 1.5 and 3T scanners from two vendors. ⋯ Brain QSM measurements have good interscanner and same-scanner reproducibility for healthy and MS subjects, respectively, on the systems evaluated in this study.
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J Magn Reson Imaging · Dec 2015
Age-dependency of glycosaminoglycan content in lumbar discs: A 3t gagcEST study.
To analyze age-dependency of glycosaminoglycan content using gagCEST (glycosaminoglycan chemical exchange saturation transfer) imaging in lumbar intervertebral discs of healthy volunteers. ⋯ We show a decreased gagCEST effect likely corresponding to decreasing glycosaminoglycans with aging. Hence, age-matched analysis of gagCEST imaging may be necessary in future studies.
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J Magn Reson Imaging · Dec 2015
Semi-automated hippocampal segmentation in people with cognitive impairment using an age appropriate template for registration.
To evaluate a new semi-automated segmentation method for calculating hippocampal volumes and to compare results with standard software tools in a cohort of people with subjective memory complaints (SMC) and mild cognitive impairment (MCI). ⋯ These results suggest that an age appropriate registration template might be a more accurate alternative to calculate hippocampal volumes when manual segmentation is not feasible.