Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Sep 2019
Diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping as a quantitative imaging biomarker for prediction of immunohistochemical receptor status, proliferation rate, and molecular subtypes of breast cancer.
Diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping is one of the most useful additional MRI parameters to improve diagnostic accuracy and is now often used in a multiparameric imaging setting for breast tumor detection and characterization. ⋯ 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:836-846.
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J Magn Reson Imaging · Sep 2019
Application of neurite orientation dispersion and density imaging to characterize brain microstructural abnormalities in type-2 diabetics with mild cognitive impairment.
Diffusion-tensor-imaging (DTI) is sensitive in detecting white matter changes in type-2 diabetes mellitus (T2DM). However, DTI indices can be affected by either neurite density or spatial variation. A novel diffusion MRI technique, termed neurite orientation dispersion and density imaging (NODDI), can provide distinct indices of fiber density and dispersion. ⋯ 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:889-898.
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Measuring T1ρ in the knee menisci can potentially be used as noninvasive biomarkers in detecting early-stage osteoarthritis (OA). ⋯ 2 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2019. J. Magn. Reson. Imaging 2019;50:824-835.
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J Magn Reson Imaging · Sep 2019
Transition zone prostate cancer: Logistic regression and machine-learning models of quantitative ADC, shape and texture features are highly accurate for diagnosis.
The limitation of diagnosis of transition zone (TZ) prostate cancer (PCa) using subjective assessment of multiparametric (mp) MRI with PI-RADS v2 is related to overlapping features between cancers and stromal benign prostatic hyperplasia (BPH) nodules, particularly in small lesions. ⋯ 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:940-950.
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J Magn Reson Imaging · Sep 2019
Simplified Luminal Water Imaging for the Detection of Prostate Cancer From Multiecho T2 MR Images.
Luminal water imaging (LWI) suffers less from imaging artifacts than the diffusion-weighted imaging used in multiparametric MRI of the prostate. LWI obtains multicompartment tissue information from a multiecho T2 dataset. ⋯ 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;50:910-917.