Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Dec 2014
Comparative Study Controlled Clinical TrialQuantification of cerebral blood flow in healthy volunteers and type 1 diabetic patients: comparison of MRI arterial spin labeling and [(15)O]H2O positron emission tomography (PET).
To compare cerebral blood flow (CBF) values measured using magnetic resonance imaging (MRI) arterial spin labeling (ASL) with those obtained with [(15)O]H2O positron emission tomography (PET), the gold standard for measuring CBF in vivo. ⋯ PCASL provides CBF values that correlate with [(15)O]H2O PET-derived values, but is less accurate. PCASL may be an attractive alternative when absolute quantification is not needed.
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J Magn Reson Imaging · Dec 2014
Relationship of MR elastography determined liver stiffness with cardiac function after Fontan palliation.
To use MR elastography to assess liver stiffness in patients with congenital heart disease palliated with the Fontan procedure and correlate findings with cardiac index and other functional parameters obtained during cardiac MRI. ⋯ MRE shows promise as a monitoring tool in the Fontan population, demonstrating an elevated liver stiffness in all patients, which inversely correlated with the MR determined cardiac index.
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J Magn Reson Imaging · Dec 2014
Implementation of two-dimensional L-COSY at 7 Tesla: an investigation of reproducibility in human brain.
To evaluate the utility of two-dimensional (2D) Localized Correlated Spectroscopy (L-COSY) in metabolic profiling of the human brain at 7 Tesla (T). ⋯ 2D L-COSY at 7 T demonstrated improved sensitivity in detecting additional metabolites with reliability comparable to established techniques at lower fields, which may aid in the metabolic assessment of diseased states.
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J Magn Reson Imaging · Dec 2014
Rapid single-breath-hold 3D late gadolinium enhancement cardiac MRI using a stack-of-spirals acquisition.
To develop a rapid single-breath-hold 3D late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) method, and demonstrate its feasibility in cardiac patients. ⋯ Stack-of-spiral acquisition combined with non-Cartesian SPIRiT parallel imaging enables rapid 3D LGE MRI in a 12 heartbeat-long breath-hold.J.
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J Magn Reson Imaging · Dec 2014
Short-term exercise-induced changes in hydration state of healthy Achilles tendons can be visualized by effects of off-resonant radiofrequency saturation in a three-dimensional ultrashort echo time MRI sequence applied at 3 Tesla.
Off-resonant RF saturation influences signal intensity dependent on free and bound water fractions as well as the macromolecular content. The extent of interaction between these compartments can be evaluated by using the off-resonance saturation ratio (OSR). Combined with UTE sequences quantification of OSR even in tendinous tissues with extremely fast signal decay is possible. The aim of this prospective study was to investigate short-term exercise-induced effects of hydration state of the Achilles tendon by means of OSR and tendon volume. ⋯ The observed decreased tendon volume and increased OSR directly after exercise indicates a short-term change in tendinous proton compartments, most likely a loss of free water molecules within the tendon.