Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Jan 2014
Comparative StudyPotential of computer-aided diagnosis of high spectral and spatial resolution (HiSS) MRI in the classification of breast lesions.
To compare the performance of computer-aided diagnosis (CADx) analysis of precontrast high spectral and spatial resolution (HiSS) MRI to that of clinical dynamic contrast-enhanced MRI (DCE-MRI) in the diagnostic classification of breast lesions. ⋯ CADx of HiSS (without contrast) performed similarly to CADx on clinical DCE-MRI; thus, computerized analysis of HiSS may provide sufficient information for diagnostic classification. The results are clinically important for patients in whom contrast agent is contra-indicated. Even in the limited acquisition mode of 2D single slice HiSS, by using quantitative image analysis to extract characteristics from the HiSS images, similar performance levels were obtained as compared with those from current clinical 4D DCE-MRI. As HiSS acquisitions become possible in 3D, CADx methods can also be applied. Because HiSS and DCE-MRI are based on different contrast mechanisms, the use of the two protocols in combination may increase diagnostic accuracy.
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J Magn Reson Imaging · Jan 2014
Comparative StudyDirect comparison of intra-articular versus intravenous delayed gadolinium-enhanced MRI of hip joint cartilage.
To investigate the potential of delayed gadolinium-enhanced magnetic resonance imaging in cartilage (dGEMRIC) after intra-articular (ia) contrast agent administration at 3 Tesla (T), a paired study comparing intravenous (iv) dGEMRIC (standard) with ia-dGEMRIC was performed. ⋯ Ia-dGEMRIC was able to reveal the characteristic T1Gd pattern in hip joint cartilage confirming the sensitivity of ia-dGEMRIC for GAG. In addition, there was a significant correlation between iv-dGEMRIC and ia-dGEMRIC. However, the T1Gd values after ia contrast media application were significantly lower than those after iv application that has to be considered for future studies.
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J Magn Reson Imaging · Dec 2013
Randomized Controlled Trial Comparative StudyHyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
To compare hyperpolarized helium-3 ((3) He) and xenon-129 ((129) Xe) MRI in asthmatics before and after salbutamol inhalation. ⋯ In asthma, hyperpolarized (129) Xe MRI may help reveal ventilation abnormalities before bronchodilation that are not observed using hyperpolarized (3) He MRI.
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J Magn Reson Imaging · Dec 2013
Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration.
To establish relationships between quantitative MRI (qMRI) and biomechanical parameters in order to help inform and interpret alterations of human intervertebral discs (IVD) with different grades of degeneration. ⋯ Our studies indicate that qMRI can be used as a noninvasive diagnostic tool in the detection of IVD properties with the potential to help interpret and detect early, middle, and late stages of degeneration. QMRI of human IVD can therefore become a very important diagnostic assessment tool in determining the functional state of the disc.
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J Magn Reson Imaging · Dec 2013
Noncontrast-enhanced magnetic resonance angiography and venography imaging with enhanced angiography.
To achieve simultaneous high-resolution magnetic resonance angiography and venography (MRAV) imaging in terms of enhanced time-of-flight (TOF) angiography and susceptibility-weighted imaging (SWI), with a clear separation of arteries and veins. ⋯ Using the proposed interleaved double-echo sequence along with the NLS postprocessing method, one can simultaneously obtain both high-quality SWI and significantly enhanced TOF MRA with clear separation of arterial and venous maps.