Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Nov 2013
Relationships between hypercarbic reactivity, cerebral blood flow, and arterial circulation times in patients with moyamoya disease.
To evaluate the correlation between angiographic measures of Moyamoya disease and tissue-level impairment from measurements of tissue perfusion and cerebrovascular reactivity (CVR). ⋯ Correlative measures between angiography and hemodynamic methods suggest that BOLD and ASL could be used for expanding the diagnostic imaging infrastructure in Moyamoya patients and potentially tracking tissue response to revascularization.
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J Magn Reson Imaging · Nov 2013
Cerebral blood flow quantification in swine using pseudo-continuous arterial spin labeling.
To develop quantitative cerebral blood flow (CBF) imaging using pseudo-continuous arterial spin labeling (PCASL) in swine, accounting for their cerebrovascular anatomy and physiology. ⋯ This study demonstrates the feasibility of PCASL for CBF quantification in swine. Quantification of CBF using PCASL in swine can be further developed as an accessible and cost-effective model of human cerebral perfusion for investigating injuries that affect blood flow.
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J Magn Reson Imaging · Nov 2013
Quantitative tractography and tract shape modeling in amyotrophic lateral sclerosis.
To investigate brain-wide white matter structural changes associated with amyotrophic lateral sclerosis (ALS) using an automatic single seed point tractography-based segmentation method, probabilistic neighborhood tractography (PNT), which provides quantitative measures of both tract integrity and shape. ⋯ ALS, although particularly affecting CST, is associated with subtle changes in white matter tract integrity and shape in several other major fibers within the brain. Correlations between CST integrity and disease progression rate suggest that quantitative tractography may provide useful biomarkers of disease evolution in ALS.
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J Magn Reson Imaging · Nov 2013
Volumetric late gadolinium-enhanced myocardial imaging with retrospective inversion time selection.
To develop and validate a novel free-breathing 3D radial late gadolinium-enhanced magnetic resonance imaging technique (3D LGE-MRI) with isotropic resolution and retrospective inversion time (TI) selection for myocardial viability imaging. ⋯ The 3D LGE-MRI technique demonstrated in this study is a promising alternative for the assessment of myocardial viability in patients who have difficulty sustaining breath-holds for the clinical standard 2D LGE-MRI.
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J Magn Reson Imaging · Nov 2013
Comparative StudyUsefulness of the SPACE pulse sequence at 1.5T MR cholangiography: comparison of image quality and image acquisition time with conventional 3D-TSE sequence.
To prospectively evaluate the image quality and image acquisition time at 3D magnetic resonance cholangiopancreatography (MRCP) using sampling perfection with application optimized contrasts (SPACE) and conventional turbo-spin-echo (TSE) sequences. ⋯ On the 1.5T MR scanner, 3D-MRCP with the SPACE sequence significantly improved the contrast and CNR of CBD. In addition, it yielded images of better quality at 30% shorter acquisition time than constant refocusing pulse flip angle TSE.