Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Jun 2007
High temporal resolution breathheld 3D FIESTA CINE imaging: validation of ventricular function in patients with chronic myocardial infarction.
To develop a gated single-breathhold, high temporal resolution three-dimensional (3D) CINE imaging technique and to evaluate its accuracy in volumetric and functional quantification in patients with chronic myocardial infarction. ⋯ High temporal resolution 3D CINE SSFP imaging of the whole heart can be obtained in a single breathhold and yield ventricular function measurements similar to 2D CINE methods.
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To evaluate the impact of data quality on the localization of brain activation in functional magnetic resonance imaging (fMRI) and to explore whether the temporal contrast-to-noise-ratio (CNR) provides a quantitative parameter to estimate fMRI quality. ⋯ Calculating the CNR using an adaptive low-pass filter gives similar results to a GLM-based approach and could be advantageous for cases in which the hemodynamic response function (HRF) differs significantly from common assumptions. The CNR can be used to identify and exclude runs with suboptimal CNR, and to identify sessions with insufficient data quality. The CNR may serve as a quantitative and intuitive parameter to assess the performance and quality of clinical fMRI investigations, including information on both functional performance (contrast) and data quality (noise caused by the system and physiology).
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J Magn Reson Imaging · Jun 2007
Insight into RF power requirements and B1 field homogeneity for human MRI via rigorous FDTD approach.
To study the dependence of radiofrequency (RF) power deposition on B(0) field strength for different loads and excitation mechanisms. ⋯ With variable phase/amplitude excitation, as a function of frequency, the peak-then-decrease relation observed in the upper axial slices of brain with quadrature excitation becomes more evident in the lower slices as well. Additionally, homogeneity optimization targeted at minimizing the ratio of maximum/minimum B(1) (+) field intensity within the region of interest, typically results in increased RF power requirements (standard deviation was not considered in this study). Increasing the number of excitation ports, however, can result in significant RF power reduction.
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J Magn Reson Imaging · Jun 2007
Rapid dark-blood carotid vessel-wall imaging with random bipolar gradients in a radial SSFP acquisition.
To investigate and evaluate a new rapid dark-blood vessel-wall imaging method using random bipolar gradients with a radial steady-state free precession (SSFP) acquisition in carotid applications. ⋯ Overall, this sequence offers a simple and effective dark-blood contrast mechanism for high-SNR SSFP acquisitions in vessel wall imaging within a short acquisition time.
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J Magn Reson Imaging · May 2007
ReviewImaging strategies to reduce the risk of radiation in CT studies, including selective substitution with MRI.
"When one admits that nothing is certain one must, I think, also admit that some things are much more nearly certain than others." Bertrand Russell (1872-1970) Computed tomography (CT) is one of the largest contributors to man-made radiation doses in medical populations. CT currently accounts for over 60 million examinations in the United States, and its use continues to grow rapidly. The principal concern regarding radiation exposure is that the subject may develop malignancies. ⋯ The FDA estimates that a CT examination with an effective dose of 10 mSv may be associated with an increased chance of developing fatal cancer for approximately one patient in 2000, whereas the BEIR VII lifetime risk model predicts that with the same low-dose radiation, approximately one individual in 1000 will develop cancer. There are uncertainties in the current radiation risk estimates, especially at the lower dose levels encountered in CT. To address what should be done to ensure patient safety, in this review we discuss the "as low as reasonably achievable" (ALARA) principle, and the use of MRI as an alternative to CT.