Fetal diagnosis and therapy
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Fetal. Diagn. Ther. · Jan 2017
Fetoscopic Endoluminal Tracheal Occlusion in Fetuses with Severe Diaphragmatic Hernia: A Three-Year Single-Center Experience.
To report on our experience in the prenatal treatment of severe congenital diaphragmatic hernia (CDH) by fetoscopic endoluminal tracheal occlusion (FETO). ⋯ In this study, FETO was associated with an infant survival of 47% in cases with isolated unilateral severe CDH. The post-FETO increase in O/E LHR was higher in fetuses that survived compared to those who died.
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Fetal. Diagn. Ther. · Jan 2017
Comparative StudyNon-Invasive Haemodynamic Monitoring in Pregnancy: A Comparative Study Using Ultrasound and Bioreactance.
Due to the importance of cardiovascular dysfunction and advances in the development and use of non-invasive cardiac output (CO) monitoring devices, there is a growing interest in their use in the obstetric population. The aim of this study was to compare two commercially available, non-invasive CO monitors in the assessment of heart rate (HR), stroke volume (SV), CO, cardiac index (CI) and total peripheral resistance (TPR) in an obstetric population. ⋯ Our findings suggest that the two methodologies perform similarly in both uncomplicated pregnancies and in pregnancies complicated by hypertensive disorders. The study findings do not preclude the use of USCOM® and NICOM® devices in pregnancy, but indicate that these platforms cannot be used interchangeably. Our findings demonstrate an improvement in MPD as gestation advances and, therefore, questions the validity of previous longitudinal studies investigating maternal haemodynamics using these methodologies. Our work also highlights the need to construct reference ranges for each device and for validation of each methodology against a reference method before their use in research or clinical practice.