Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
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Anasthesiol Intensivmed Notfallmed Schmerzther · Sep 1996
Comparative Study[Ventilation via a transnasally placed pharyngeal tube. Comparison with mask ventilation].
The present prospective study was designed to investigate the respiratory function during ventilation via a tube inserted through the nose into the pharynx. Results were compared with respiratory parameters measured during conventional mask ventilation in the same patients. ⋯ The use of a pharyngeally placed tube proved adequate compared to conventional mask ventilation in 20 patients without underlying airway disease.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Sep 1996
[Patient knowledge concerning anesthesia general practice and the responsibilities of the anesthetist].
In two Austrian university hospitals 104 patients were interviewed on the basis of questionnaires about their knowledge of the role of anaesthetists. Although 93% of the Patients considered anaesthesists to be physicians, major deficits were found regarding the knowledge about the spheres of activities of anaesthetists. 60% of the respondents confined the anaesthetist to the operating theatre. ⋯ To current practice of informing the patient calls for improvement and new approaches. In addition to this further evaluation work on the influence of the mass media and public knowledge about anaesthesia and the anaesthetists' role should be undertaken.
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Anasthesiol Intensivmed Notfallmed Schmerzther · Aug 1996
Review[What significance to genotype changes have in diagnosis of malignant hyperthermia?].
Malignant hyperthermia (MH) is a potentially fatal, inherited pharmacogenetic disorder characterised by a dysfunction of the intracellular calcium regulation. Linkage to DNA markers from the chromosome 19q12-13.2 region and the MHS-phenotype (MH susceptible) has been shown in about 50% of families with a history of MH. The ryanodine receptor gene encoding the human skeletal muscle ryanodine receptor has been localised to the chromosome 19q13.1-13.2 region. ⋯ However, the relevance of this observation is so far unknown. At present, unambiguous preoperative screening of MH disposition based on molecular genetic characteristics is not available because of the enormous heterogeneity of the human MH syndrome. Thus, the halothane-caffeine in-vitro contracture test according to the standard protocol of the "European MH Group" must be performed in order to discover MH susceptibility.