Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Dec 1999
Randomized Controlled Trial Clinical TrialA randomized, blinded trial of the antioxidant pegorgotein: no reduction in neuropsychological deficits, inotropic drug support, or myocardial ischemia after coronary artery bypass surgery.
To determine whether patients receiving pegorgotein preoperatively would be less likely than patients receiving placebo to demonstrate postoperative cerebral or myocardial dysfunction and thus would be less likely to (1) demonstrate a decline in neuropsychologic testing after cardiopulmonary bypass, (2) receive inotropic drug support, or (3) demonstrate electrocardiographic signs of ischemia or infarction. ⋯ This study showed no positive influence of pegorgotein on the incidence of any of the findings and showed a trend toward an increased incidence of myocardial ischemia or infarction.
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J. Cardiothorac. Vasc. Anesth. · Dec 1999
Clinical TrialIncreased extracellular brain water after coronary artery bypass grafting is avoided by off-pump surgery.
To determine if coronary artery bypass graft (CABG) surgery without cardiopulmonary bypass (CPB) avoids the brain swelling known to occur after CPB, to quantify these brain water compartment changes, and to identify the water shifts as due to intracellular or extracellular water. ⋯ Changes consistent with increased extracellular brain water seen after CABG with CPB were not observed in patients undergoing CABG without CPB. The clinical significance of brain water changes and increased brain water content after surgery with CPB remains undefined.
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J. Cardiothorac. Vasc. Anesth. · Dec 1999
A multidisciplinary process to improve the efficiency of cardiac operating rooms.
To alter the approach to cardiac operating room services in an attempt to remain competitive in a cost-driven market. ⋯ Development of a working group, with support from the hospital administration, can significantly decrease the time of tasks in a cardiac surgery operating room without adversely affecting morbidity and mortality.
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J. Cardiothorac. Vasc. Anesth. · Dec 1999
Letter Case ReportsPostoperative delirium and defibrillation.