Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2001
Randomized Controlled Trial Clinical TrialThe effects of fenoldopam on coronary conduit blood flow after coronary artery bypass graft surgery.
To quantify the effects of fenoldopam, 0.1 microg/kg/min, on left internal mammary artery (LIMA) and saphenous vein blood flow after coronary anastomosis. ⋯ The findings indicate that fenoldopam, 0.1 microg/kg/min, did not influence coronary conduit blood flow to a clinically significant extent. The small increase in LIMA blood flow may be of greater importance in high-risk patients or in the prevention of coronary arterial spasm.
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J. Cardiothorac. Vasc. Anesth. · Feb 2001
Randomized Controlled Trial Clinical TrialElectric impedance for evaluation of body fluid balance in cardiac surgical patients.
To evaluate whether electric impedance can be used to monitor body fluid balance and fluid distribution in cardiac surgical patients. ⋯ Alterations in electric impedance closely follow changes in fluid balance during the perioperative period. This method can be used in clinical practice to control postoperative body fluid balance in cardiac surgical patients.
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J. Cardiothorac. Vasc. Anesth. · Feb 2001
Another point of view on the mechanism of thrombin generation during cardiopulmonary bypass: role of tissue factor pathway inhibitor.
To determine the role of tissue factor and tissue factor pathway inhibitor (TFPI) in coagulation activation during cardiopulmonary bypass (CPB). ⋯ These data indicate that TFPI release by heparin probably has an important role in the suppression of the tissue factor-dependent coagulation pathway during CPB. These changes occur along with ongoing thrombin generation and its activation. Either insufficient prevention of thrombin generation by TFPI or indirect activation of the intrinsic coagulation pathway occurs during CPB.
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J. Cardiothorac. Vasc. Anesth. · Feb 2001
Comparative Study Clinical TrialA comparison of neuropsychologic deficits after extracardiac and intracaradiac surgery.
To compare the incidence of neuropsychologic deficits 1 week and 6 months after coronary artery bypass graft (CABG) surgery (extracardiac) and valve surgery with or without CABG surgery (intracardiac) using reliable change indices to define the incidence of neuropsychologic deficits. ⋯ There are some differences in the neuropsychologic outcome of extracardiac and intracardiac surgery. Patients undergoing isolated CABG surgery showed a greater reduction in the incidence of persisting deficits at 6 months than patients undergoing valve surgery with or without CABG surgery. This finding warrants further investigation, with particular attention to patients undergoing combined valve and coronary artery procedures.