Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialHypertonic saline (7.5%) decreases perioperative weight gain following cardiac surgery.
To compare the effects of 7.5% hypertonic saline (HS) and 0.9% normal saline (NS) on perioperative weight gain in cardiac surgical patients. ⋯ HS had an intense diuretic effect, which reduced intraoperative fluid retention. This effect was confirmed by the lesser increase in body weight measured on the first postoperative morning.
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Clinical TrialHeparin-bonded cardiopulmonary bypass circuits reduce cognitive dysfunction.
To determine the incidence of cerebral dysfunction in cardiac surgical patients exposed to heparin-bonded cardiopulmonary bypass (HB-CPB) versus nonheparin-bonded cardiopulmonary bypass (NH-CPB) circuits through neuropsychometric testing and to correlate these findings with markers of the systemic inflammatory response to CPB. ⋯ Patients undergoing cardiac surgery with CPB have less postoperative cognitive dysfunction during CPB when HB-CPB circuits are employed. Although there was a relationship, this finding did not correlate with decreased complement activation intraoperatively and activation of coagulation postoperatively.
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J. Cardiothorac. Vasc. Anesth. · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialPostoperative pulmonary function in coronary artery bypass graft surgery patients undergoing early tracheal extubation: a comparison between short-term mechanical ventilation and early extubation.
To evaluate the effect of a short period of mechanical ventilation (3 hours) versus immediate extubation (within 1 hour of surgery) on pulmonary function, gas exchange, and pulmonary complications after coronary artery bypass graft (CABG) surgery. ⋯ The data suggest that extending mechanical ventilation after CABG surgery does not affect pulmonary function. Provided that routine extubation criteria are met, patients can be safely extubated early (within 1 hour) after major cardiac surgery without concerns of further pulmonary derangement.