Journal of cardiothoracic and vascular anesthesia
-
J. Cardiothorac. Vasc. Anesth. · Jun 2003
Randomized Controlled Trial Comparative Study Clinical TrialEffects of thoracic epidural meperidine on arterial oxygenation during one-lung ventilation in thoracic surgery.
To compare the effects that the use of general intravenous anesthesia (propofol-fentanyl) (GA) or general anesthesia combined with thoracic epidural anesthesia with meperidine (TEA-M) may have on arterial oxygenation during one-lung ventilation (OLV). ⋯ It is concluded that GA combined with TEA-M (2 mg/kg) do not affect arterial oxygenation during OLV in thoracic surgery.
-
J. Cardiothorac. Vasc. Anesth. · Jun 2003
Randomized Controlled Trial Comparative Study Clinical TrialChoice of opioid supplementation for day-case rigid bronchoscopy:a randomized placebo-controlled comparison of a bolus of remifentanil and alfentanil.
To compare the efficacy of different bolus doses of remifentanil, alfentanil, and saline at controlling the hemodynamic responses to day-case rigid bronchoscopy under general anesthesia. ⋯ A bolus of 2 micro g/kg of remifentanil successfully attenuated the hemodynamic response to rigid bronchoscopy without delaying recovery.
-
J. Cardiothorac. Vasc. Anesth. · Jun 2003
Comparative StudyChronic exposure to nicotine does not prevent neurocognitive decline after cardiac surgery.
To establish the association between smoking and cognitive decline in patients undergoing coronary artery bypass graft (CABG) surgery. ⋯ This study confirmed previous findings that age, baseline cognitive function, years of education, and impaired left ventricular function are independent predictors of neurocognitive decline at 6 weeks after CABG surgery. Smoking is neither preventive nor causative of cognitive decline after CABG surgery.
-
J. Cardiothorac. Vasc. Anesth. · Jun 2003
Randomized Controlled Trial Comparative Study Clinical TrialEffect of site of venous protamine administration, previously alleged risk factors, and preoperative use of aspirin on acute protamine-induced pulmonary vasoconstriction.
To determine whether the incidence of protamine-induced pulmonary vasoconstriction (PIPV) is influenced by central venous versus peripheral venous infusion of protamine and whether aspirin ingestion within a week of surgery would decrease the incidence of PIPV. ⋯ Although the site of venous protamine administration does not influence incidence of PIPV, aspirin ingestion within 1 week of surgery may decrease it. These data also confirmed other studies suggesting that previous protamine administration predisposes to this protamine reaction.
-
J. Cardiothorac. Vasc. Anesth. · Jun 2003
Randomized Controlled Trial Comparative Study Clinical TrialProtective effect of antioxidants on pulmonary endothelial function after cardiopulmonary bypass.
Pulmonary endothelium-dependent vasodilation is impaired after cardiopulmonary bypass. One explanation might be the generation of reactive oxygen species during the period without flow in the pulmonary artery. The aim of the current study was to investigate if treatment with antioxidants could improve pulmonary endothelial function after cardiopulmonary bypass and influence the blood oxidative status. ⋯ The better maintained endothelium-dependent vasodilation after cardiopulmonary bypass in the treatment group indicated that antioxidant therapy reduced endothelial dysfunction.