Journal of cardiothoracic and vascular anesthesia
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J. Cardiothorac. Vasc. Anesth. · Apr 2005
Normobaric hyperoxia reduces cardiac index in patients after coronary artery bypass surgery.
The purpose of this study was to assess the hemodynamic changes in response to normobaric hyperoxia in patients immediately after coronary artery bypass surgery. ⋯ Exposing patients after coronary artery surgery to hyperoxia induces significant hemodynamic changes.
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J. Cardiothorac. Vasc. Anesth. · Apr 2005
The mechanisms of the direct vascular effects of fentanyl on isolated human saphenous veins in vitro.
The purpose of this study was to determine the mechanism of the direct effects of fentanyl on human veins in vitro. ⋯ The present results show that fentanyl causes vasodilatation via both endothelium- and opioid receptor-independent mechanisms in the human saphenous vein. The relaxant effects of fentanyl are probably via activation of K+ channel and Na+K+-adenosine trisphosphatase and inhibition of Ca++ channel.
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J. Cardiothorac. Vasc. Anesth. · Apr 2005
Comparative Study Clinical TrialIntraoperative glucose control in diabetic and nondiabetic patients during cardiac surgery.
The purpose of this study was to evaluate intraoperative glucose control. ⋯ Adequate glycemic control can be achieved in most diabetics during cardiac surgery using a modified insulin clamp technique provided initial glucose is <300 mg/dL.
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J. Cardiothorac. Vasc. Anesth. · Apr 2005
Clinical TrialAnalysis of diastolic function in patients undergoing aortic aneurysm repair and impact on hemodynamic response to aortic cross-clamping.
The purpose of this study was to analyze left ventricular diastolic function in patients undergoing aortic aneurysm repair and to investigate the effects of laparotomy and aortic cross-clamping on diastolic function. ⋯ About 50% of patients undergoing aortic aneurysm repair exhibit signs of diastolic dysfunction. The majority of these patients showed delayed relaxation. Patients with pseudonormal filling displayed a significantly lower cardiac index. Laparotomy resulted in an improvement in diastolic function in about half of patients with preexisting diastolic dysfunction. The effects of cross-clamping on diastolic function are minimal.