Journal of cardiothoracic and vascular anesthesia
The most recent articles from:
J. Cardiothorac. Vasc. Anesth.
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J. Cardiothorac. Vasc. Anesth. · Sep 2023
Observational StudyDevelopment of New Donor-Specific and Human Leukocyte Antigen Antibodies After Transfusion in Adult Lung Transplantation.
The development of new human leukocyte antigens (HLAs) and donor-specific antibodies (DSAs) in patients are associated with worse outcomes following lung transplantation. The authors aimed to examine the relationship between blood product transfusion in the first 72 hours after lung transplantation and the development of HLA antibodies, including DSAs. ⋯ Increased perioperative transfusion of platelets and cryoprecipitate are associated with de novo HLA and DSA development, respectively, in lung transplant recipients during the first year after transplantation.