Cerebral cortex
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One feature of the cerebral cortex circuitry is the complex network of fibers which links its different functional regions. Our knowledge of the specific relationships between neurons which form these pathways is limited. The cortico-cortical connections between primary somatosensory cortex (SI) and primary motor cortext (MI) were the focus of the study. ⋯ This aspect of the connection may exemplify a unique feature of the cortical circuit which helps to define its functional role. The significance of these results in defining cortical function is that the particular cortical circuit described may provide an anatomical substrate for the modulation of motor cortex activity by integrated signals from the sensory cortex. The synaptic relationships of neurons in this pathway may be characteristic of i