Current opinion in neurobiology
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Curr. Opin. Neurobiol. · Oct 1999
ReviewSense and specificity: a molecular identity for nociceptors.
Recent cloning efforts have identified families of ligand- or voltage-gated ion channels that are expressed by pain-sensing primary afferent neurons. Pharmacological, electrophysiological and genetic studies are beginning to reveal how these signaling molecules specify roles for subsets of sensory neurons in the pain pathway.