Cardiology in the young
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Cardiology in the young · Mar 2002
Comparative StudySoluble endothelial adhesion molecules during paediatric cardiovascular surgery with or without cardiopulmonary bypass.
Paediatric cardiovascular surgery with or without cardiopulmonary bypass induces a complex pattern of pro- and anti-inflammatory responses. It is suspected that they may contribute to changes on the vascular endothelium. The endothelial response to cardiosurgical trauma and cardiopulmonary bypass, especially in children, has yet to be well established. ⋯ Endothelial activation of release of adhesion molecules is reduced during paediatric cardiovascular surgery. Endothelial activity is more perturbed with cardiopulmonary bypass and for a long time after surgery.