International journal of obstetric anesthesia
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In 1993 a postal survey of maternity hospitals within the UK was carried out to obtain data on the types of anaesthesia used for caesarean section. The poor response rate (79/226, 35%) reflects the paucity of data available in many centres. ⋯ Overall, during the 11-year period covered by the survey there was a significant reduction in the percentage use of general anaesthesia (77% in 1982 declining to 44% in 1992), but because of a 51% increase in the caesarean section rate the real reduction in the actual number of general anaesthetics used was modest (13%). If this holds true nationally, then factors other than a simple change from general anaesthesia to regional anaesthesia must contribute to the reduced maternal mortality from anaesthetic causes.
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Int J Obstet Anesth · Oct 1995
Effect of adrenaline on plasma concentrations of fentanyl during epidural anaesthesia for caesarean section.
The present study was designed to assess the effect of adrenaline on the plasma concentrations of fentanyl in mothers and umbilical vessels after epidural administration for caesarean section. Thirty patients undergoing elective caesarean section were allocated randomly into two groups. Group 1 (n = 16) received 100 microg fentanyl, 10 ml of 0.5% bupivacaine and 10 ml 2% lidocaine, while group II (n = 14) received 100 microg fentanyl, 10 ml of 0.5% bupivacaine with adrenaline 1:200 000, and 10 ml of 2% lidocaine with adrenaline 1:80 000. ⋯ In umbilical vessels, plasma fentanyl concentrations were comparable in the two groups: (0.12 +/- 0.08 ng ml(-1) and 0.13 +/- 0.08 ng ml(-1) in UV and 0.08 +/- 0.07 ng ml(-1) and 0.06 +/- 0.05 ng ml(1) in UA of groups I and II respectively). The maximum plasma concentration in UV was 0.24 ng ml(-1) in group I and 0.25 ng ml(-1) in group II. There was no significant correlation between umbilical vessel (vein or artery):MV ratio and dose to delivery interval and no difference between the two groups in Apgar score or umbilical cord pH.
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In the following case there was delay in diagnosing uterine rupture in a patient with an epidural in situ. The danger of using large doses of local anaesthetics and opioids epidurally in patients who have had previous caesarean sections is discussed.