American heart journal
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American heart journal · Sep 2002
Comparative StudyImpact of disease activity on left ventricular performance in patients with acromegaly.
In patients with acromegaly, abnormalities of systolic and diastolic left ventricular (LV) performance, mostly associated with hypertension or LV hypertrophy, have been reported. We used 2-dimensional/Doppler echocardiographic methods and tissue Doppler imaging (TDI) to elucidate the impact of disease activity on LV function in patients with acromegaly. ⋯ Disease activity has a significant impact on LV performance in patients with acromegaly. In subjects with active disease, diastolic dysfunction and beginning impairment of overall LV performance are present. In patients with cured/well-controlled disease, systolic and diastolic function appear normal.
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American heart journal · Sep 2002
Editorial Comment Comparative StudyReperfusion in waiting: what queue should we join?