American heart journal
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American heart journal · Jun 2004
Multicenter Study Clinical TrialImpact of age, race, and sex on the ability of B-type natriuretic peptide to aid in the emergency diagnosis of heart failure: results from the Breathing Not Properly (BNP) multinational study.
B-type natriuretic peptide (BNP) is secreted from the cardiac ventricles in response to increased wall tension. ⋯ If one assumes that failing to treat cases of CHF is worse than treating negative cases, then relatively low BNP cut-points (eg, not >100 pg/mL) should be used in patients presenting to the Emergency Department with a chief complaint of dyspnea, regardless of age, sex, or ethnicity.